Ob-Ugric database

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The developments, uses, and functions of preverbal particles in Hungarian and other Uralic languages

Within the Uralic language family, preverbal particles generally only occur within the Ugric branch of the Finno-Ugric languages, a fact known for some time (cf. Zsirai, 1933). Most Uralic scholars (who assume the existence of proto-Uralic) assume that preverbal particles are not a Uralic feature, that is, the existence of these particles in a handful of Uralic languages is due to innovations i...

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Impaired Muscle Regeneration in Ob/ob and Db/db Mice

In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be required, not only for restoring muscle structure and function, but also for maintaining exercise capacity and insulin sensitivity. The hypothesis of this study was that muscle regeneration would be impaired in ob/ob and db/db mice, which are common mouse models of obesity and type 2 diabetes. Muscle injury...

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Wnt10b inhibits obesity in ob/ob and agouti mice.

The Wnt family of secreted signaling molecules has profound effects on diverse developmental processes, including the fate of mesenchymal progenitors. While activation of Wnt signaling blocks adipogenesis, inhibition of endogenous Wnt/beta-catenin signaling by Wnt10b promotes spontaneous preadipocyte differentiation. Transgenic mice with expression of Wnt10b from the FABP4 promoter (FABP4-Wnt10...

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Hypothalamic neuronal activity and intermediary metabolism in ob/ob mice

Introduction: Obesity is a pandemic syndrome, associated with the most prevalent and mortal pathologies in developed countries (Rajala and Scherer, 2003). This pathology results from an imbalance in the control of food intake and energy homeostasis as regulated by a complex network of peripheral and intra-hypothalamic signalling systems (Schwartz et al., 2000). On this basis, the investigation ...

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Glucocerebroside ameliorates the metabolic syndrome in OB/OB mice.

Glucocerebroside (GC) is a naturally occurring glycolipid that may alter natural killer T (NKT) cell function. To determine the effect of GC on the metabolic derangements and immune profile in leptin-deficient mice, Ob/Ob mice were treated by daily injections of GC for 8 weeks and followed for various metabolic and immunological parameters. Marked amelioration of the metabolic alterations chara...

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ژورنال

عنوان ژورنال: Acta Linguistica Academica

سال: 2017

ISSN: 2559-8201

DOI: 10.1556/2062.2017.64.3.4